ENHPATHY – Molecular basis of human enhanceropathies

A European Training Network (MSCA)

WE ARE ENHPATHY >

Deciphering the molecular basis of human enhanceropathies

STUDYING ENHANCERS AT ALL SCALES >

15 students 15 World renowned research organisations 1 topic : epigenetics

TRAINING THE NEW GENERATION OF EXPERTS >

Spreading discovery to the world

REVEALING TALENTS >

RT @Frances83744189 Here my first post for "All Eyes On Enhancers" #AEOE blog by @enhpathy_H2020 about my PhD project. @ABioDesign @MSCActions #enhanceropathies enhpathy.eu/sfa-post/uncov…

About 2 weeks ago from ENHPATHY's Twitter via Twitter for iPhone

RT @Frances83744189 Ready to dive into art thanks to the Enhancer in art program #EIA by @enhpathy_H2020 ! #enhanceropathies #SciArt @MSCActions @EU_H2020 Have a look at my new post ⬇️⬇️ enhpathy.eu/eia-post/scien…

About 3 weeks ago from ENHPATHY's Twitter via Twitter for iPhone

The #EIA program is a substantial opportunity to communicate great science to diverse audiences including students of all levels as well as the general public. Congratulations @OlgaPushkarev for your first #EIA post! twitter.com/OlgaPushkarev/…

Last month from ENHPATHY's Twitter via Twitter Web App

Enhancer In Art (#EIA) is a science and art program sharing scientific news from @enhpathy_H2020 with the general public. In the coming months, our PhD fellows will team up with local artists to sparkle creative art. Congratulations @vartikabisht for your first EIA post! twitter.com/vartikabisht/s…

Last month from ENHPATHY's Twitter via Twitter Web App

RT @vartikabisht Just published my first #AEOE blog on the @enhpathy_H2020 website giving insights on Congenital Heart disease and highlighting the significance of my PhD project in the early detection of the disease. @EU_H2020 @MSCActions enhpathy.eu/?p=3716

About a month ago from ENHPATHY's Twitter via Twitter for iPhone

RT @KajaMadsen Just shared the first post on my blog. Really excited about this challenge from @enhpathy_H2020. Especially looking forward to following the blogs from the other ENHPATHY members. enhpathy.eu/sfa-post/welco… @EU_H2020 @MSCActions #enhanceropathies

About a month ago from ENHPATHY's Twitter via Twitter Web App

RT @PIPgen_ITN This project receives funding from the @EU_H2020 Research & Innovation Programme. Any related tweets reflect only the views of the project owner.

About 2 months ago from ENHPATHY's Twitter via Twitter Web App

NEWSROOM

EMBO workshop, October 6-9, 2021 | Santander Spain

Introduction Retreat (Event II) – Feb 1-5, 2021

Kickoff meeting …checked! Enhpathy officially launched its program.

The (MSCA)-ITN the Innovative Training Networks program ENHPATHY to be launched on March 01, 2020

MORE NEWS

EVENTS

ABOUT US

Training the new generation of researchers on the molecular basis of human enhanceropathies. Opening new diagnostic and therapeutic avenues for patients.

ENHPATHY is a multidisciplinary science consortium created in the frame of the Marie Sklodowska-Curie actions (MSCA)-ITN-ETN European Training Networks call and regrouping 15 academic and 9 non-academic European organisations in the continuum of basic, translational and clinical research on enhancers and associated diseases.

MORE INFO

ESR 1 project : Dissection of coordinated stress responses by novel promoter elements with enhancer activity (WP1)
Supervisor : SALVADOR SPICUGLIA
Coordinator & WP7 Leader
Institute Nationale pour la Santé et la Recherche Médicale (Inserm)

Theory and Approaches of Genomic Complexity (TAGC)

ESR 2 project : Modeling gene-environmental interactions implicated in the etiology of human neurocristopathies (WP3)
Supervisor : ALVARO RADA IGLESIAS
Vice-coordinator & WP4 Leader.
University of Cantabria

Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC)

ESR 3 project : Genetic and epigenetic changes in hematopoietic stem cells (HSCs) during chronic inflammation (WP3)
Supervisor : MERITXELL ALBERICH-JORDA
WP5 Leader
Institute of Molecular Genetics, Prague, Czech Republic

Institute Molecular Genetics Department of Hemato-oncology

ESR 4 project : The impact of genetic variants on regulatory activities (WP1)
Supervisor : ROBIN ANDERSSON
University of Copenhagen

The andersson lab

ESR 5 project : Understanding the impact of gene regulatory variation on disease using variable chromatin modules (VCMs) (WP2)
Supervisor : BART DEPLANCKE
Swiss Federal Institute of Technology, Lausanne

School of Life Sciences

ESR 6 project : Functional assessment of candidate pathogenic enhancer mutations in patients with monogenic diabetes (WP3)
Supervisor: JORGE FERRER
WP3 Leader

Centre for Genomic Regulation

ESR 7 project : Higher-order topological organization of super-enhancer hubs, Epromoters and TADs (WP2)
Supervisor : WOUTER DE LAAT
Hubrecht Institute

Royal Netherlands Academy of Arts and Sciences

ESR 8 project : Enhancer networks in the control of lineage determination of human mesenchymal stem cells (hMSCs) (WP2)
Supervisor: SUSANNE MANDRUP
WP2 Leader

University of Southern Denmark

ESR 9 project : Analysis of the role of coregulators in the activity of cis-regulatory elements in response to inflammatory stimulation (WP1)
Supervisor: GIOCCHINO NATOLI
WP1 Leader

European Institute of Oncology (IEO)

ESR 10 project : The spatial organization of enhancers around promoter regions within chromatin contact domains for selected Human cell lines: structural regulatory landscape (WP2)
Supervisor: DARIUSZ PLEWCZYNSKI
University of Warsaw

Centre of New Technologies (UW)

ESR 11 project : Functional understanding of synergistic effects of enhancer elements at the onset of atherosclerosis (WP3)
Supervisor: PELIN SAHLÉN
Royal Institute of Technology, Stockhholm

Science for life Laboratory

ESR 12 project : Regulatory network guiding stem cell interactions within the hematopoietic niche using single cell genomics (WP1)
Supervisor: JUDITH ZAUG
European Molecular Biology Laboratory

European Molecular Biology Laboratory

ESR 13 project : Functional annotation 10 human genomes to aid the identification of disease-causing non-coding sequence variants (WP1)
Supervisor: JORIS VAN ARENSBERGEN
Legal Supervisor: SALVATORE SPICUGLIA

Gen-X B.V.

ESR 14 project : Microfluidic systems for encapsulation of molecular complexes (WP2)
Supervisor: JULIA SEPULVEDA DIAZ
Legal Supervisor: PELIN SAHLÉN

Elvesys SASv

ESR 15 project : Uncovering drug-adaptive epigenetic response in Acute Myeloid Leukemia (AML) (WP3)
Supervisor: MILEIDYS PEREZ
Legal Supervisor: SALVATORE SPICUGLIA

Advanced Biodesign

TEAM

Julia Sepulveda (Supervisor)

ELVESYS SAS (Elvesys), France

Anna-Karina Felder (ESR7)

«Higher-order topological organization of super-enhancer hubs, Epromoters and TADs (WP2)»

Artemy Zhigulev (ESR11)

«Functional understanding of synergistic effects of enhancer elements at the onset of atherosclerosis (WP3)»

Joris van Arensbergen (Supervisor)

CEO & Founder of Annogen

Meritxell Alberich-Jorda (Supervisor)

Institute of Molecular Genetics of the AS CR (IMG), Czech Republic / WP 5 Leader

CHECK ALL PROFILES

RESEARCH

Providing early-stage researchers with a multidisciplinary training in which cutting-edge genomics and genome editing approaches are combined with various in vitro and in vivo disease models to increase our understanding of the molecular basis of human enhanceropathies.

The scientific goals of ENHPATHY are to identify key deregulated enhancers and regulatory mechanisms, and provide new biomarkers and therapeutic avenues for enhanceropathies. To achieve this goal, ENHPATHY has set up an innovative, integrated and disease-focused research programme that brings together European leaders in enhancer biology, computational biology and human genetics….

KEY FIGURES

year training program

research projects

training modules

academics &

non-academics European organisations

countries

COMMUNICATION – DISSEMINATION (by PhD fellows)

ENHANCER IN ART

Enhancer in art is a science’art program offering one artist the unique opportunity to become an actor of an european scientific program, by creating an original artwork in collaboration with one of our PhD fellows.

Art and science go hand in hand in understanding the world

Science and art: the fusion of two universes

ALL EYES ON ENHANCERS

All eyes on enhancers is a blog dedicated to dissemination, defined in a scientific context, as making projects results available to the scientific community, policy makers and industry.

Uncovering drug-adaptive epigenetic response in Acute Myeloid Leukaemia (AML)

Enhancers

QUESTION ABOUT ENHPATHY?

LET’S TALK!

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 860002. The information contained in this website reflects only the authors’ view. REA and EC are not responsible for any use that may be made of this information.