Deciphering the molecular basis of human enhanceropathies
STUDYING ENHANCER AT ALL SCALES >
15 students 15 World renowned research organisations 1 topic : epigenetics
TRAINING THE NEW GENERATION OF EXPERTS >
ABOUT US
Training the new generation of researchers on the molecular basis of human enhanceropathies. Opening new diagnostic and therapeutic avenues for patients.
ENHPATHY is a multidisciplinary science consortium created in the frame of the Marie Sklodowska-Curie actions (MSCA)-ITN-ETN European Training Networks call and regrouping 15 academic and 9 non-academic European organisations in the continuum of basic, translational and clinical research on enhancers and associated diseases.
ESR 1 project : Dissection of coordinated stress responses by novel promoter elements with enhancer activity (WP1)
ESR 5 project : Understanding the impact of gene regulatory variation on disease using variable chromatin modules (VCMs) (WP2)
ESR 9 project : Analysis of the role of coregulators in the activity of cis-regulatory elements in response to inflammatory stimulation (WP1)
ESR 10 project : The spatial organization of enhancers around promoter regions within chromatin contact domains for selected Human cell lines: structural regulatory landscape (WP2)
ESR 11 project : Functional understanding of synergistic effects of enhancer elements at the onset of atherosclerosis (WP3)
ESR 12 project : Regulatory network guiding stem cell interactions within the hematopoietic niche using single cell genomics (WP1)RESEARCH
Providing early-stage researchers with a multidisciplinary training in which cutting-edge genomics and genome editing approaches are combined with various in vitro and in vivo disease models to increase our understanding of the molecular basis of human enhanceropathies.
The scientific goals of ENHPATHY are to identify key deregulated enhancers and regulatory mechanisms, and provide new biomarkers and therapeutic avenues for enhanceropathies. To achieve this goal, ENHPATHY has set up an innovative, integrated and disease-focused research programme that brings together European leaders in enhancer biology, computational biology and human genetics….
KEY FIGURES
year training program
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non-academics European organisations
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QUESTION ABOUT ENHPATHY?
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 860002. The information contained in this website reflects only the authors’ view. REA and EC are not responsible for any use that may be made of this information.