• MEMBERS ACCESS
Members area access
ENHPATHY
  • TEAM
  • RESEARCH
  • TRAINING
    • RESEARCH SKILLS
    • TRANSFERABLE SKILLS
  • COMMUNICATION & DISSEMINATION
    • ENHANCER IN ART
    • ALL EYES ON ENHANCERS
  • NEWSROOM
    • EVENTS
  • ABOUT
    • CONSORTIUM
    • GOVERNANCE
    • PUBLICATIONS
    • RESOURCES
    • CONTACT
  • MEMBERS AREA
    • Cloud Storage
    • Videoconferences
    • Directory
  • Search
  • Menu Menu

Epromoters: The regulation of gene expression is no longer a binary issue

Non classé

In all mammals, the cellular operation responsible for the maintenance of homeostasis, specifically of all the physiological balances ensuring the vital functions of an organism, is dictated by the reading of information carefully preserved in the genetic heritage or DNA. The expression of a gene that will code for one or more proteins of interest is therefore a strategic step, controlled by the presence on this DNA of regulatory sequences, which in the event of malfunction, can cause the occurrence of serious genetic pathologies, such as inflammation or auto-immune diseases.

 

Listed in two distinct families according to their locations near or far from the genes that they regulate, researchers speak of promoters or enhancers, respectively. These sequences are scrutinized by the scientific community in an attempt to arrive at a better understanding of the complexity of their modes of action. The latest work from a research team within the TAGC laboratory (Theories and Approaches to Genomic Complexity, Inserm/AMU), led by Dr. Spicuglia and published in the journal Nature Communications have recently shed new light on the role of a particular family of promoters called Epromoter that are involved in gene regulation, but this time, without particular location criteria.

Read more

 

9 February 2022/by KOM Agency
Share this entry
  • Share on Facebook
  • Share on Twitter
  • Share on LinkedIn
  • Share by Mail
https://www.enhpathy.eu/wp-content/uploads/2022/02/New-Publication.jpg 800 800 KOM Agency https://www.enhpathy.eu/wp-content/uploads/2019/11/logo-enhpathy-1.png KOM Agency2022-02-09 11:47:422022-02-09 11:47:42Epromoters: The regulation of gene expression is no longer a binary issue

LATEST NEWS

ENHPATHY highlighted in the Winter issue of EU Research

Pitch my Enhancer in art project in 90 seconds

Current challenges in understanding the role of enhancers in disease

Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway

QUESTION ABOUT ENHPATHY?

LET’S TALK!

Marie CurieThis project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 860002. The information contained in this website reflects only the authors’ view. REA and EC are not responsible for any use that may be made of this information.

© Copyright - ENHPATHY
  • Twitter
  • Facebook
  • LinkedIn
  • Vimeo
  • SiteMap
  • Legal Notice
The EMBO workshop starts today ENHPATHY ESRs visit the Novartis Institutes for BioMedical Research (NIBR)
Scroll to top

This site uses cookies. By continuing to browse the site, you are agreeing to our use of cookies.

Accept settingsHide notification onlyParamètres

Cookie and Privacy Settings



How we use cookies

We may request cookies to be set on your device. We use cookies to let us know when you visit our websites, how you interact with us, to enrich your user experience, and to customize your relationship with our website.

Click on the different category headings to find out more. You can also change some of your preferences. Note that blocking some types of cookies may impact your experience on our websites and the services we are able to offer.

Essential Website Cookies

These cookies are strictly necessary to provide you with services available through our website and to use some of its features.

Because these cookies are strictly necessary to deliver the website, refuseing them will have impact how our site functions. You always can block or delete cookies by changing your browser settings and force blocking all cookies on this website. But this will always prompt you to accept/refuse cookies when revisiting our site.

We fully respect if you want to refuse cookies but to avoid asking you again and again kindly allow us to store a cookie for that. You are free to opt out any time or opt in for other cookies to get a better experience. If you refuse cookies we will remove all set cookies in our domain.

We provide you with a list of stored cookies on your computer in our domain so you can check what we stored. Due to security reasons we are not able to show or modify cookies from other domains. You can check these in your browser security settings.

Other external services

We also use different external services like Google Webfonts, Google Maps, and external Video providers. Since these providers may collect personal data like your IP address we allow you to block them here. Please be aware that this might heavily reduce the functionality and appearance of our site. Changes will take effect once you reload the page.

Google Webfont Settings:

Google Map Settings:

Google reCaptcha Settings:

Vimeo and Youtube video embeds:

Privacy Policy

You can read about our cookies and privacy settings in detail on our Privacy Policy Page.

Legal Notice
Accept settingsHide notification only